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1Q26 results: small molecule D&M fuelling overall growth

1Q26 results: small molecule D&M fuelling overall growth

研报

1Q26 results: small molecule D&M fuelling overall growth

  药明康德(603259)   WuXi AppTec released better-than-expected 1Q26 financial results. Revenuegrew by 28.8% YoY to RMB12.4bn with continuing operations revenue increasingby 39.4% YoY, while adj. non-IFRS attributable net profit surged 71.7% YoY toRMB4.6bn. 1Q26 revenue/ adj. net profit represent 24.1%/ 25.6% of our full-yearforecasts, respectively, significantly higher than the historical average of 18-20%.As of 1Q26, backlog for continuing operations grew by 23.6% YoY (+29% YoY ifexcl. FX fluctuations) to RMB59.8bn, with new orders signed in 1Q26 growing byover 25%. Mgmt. maintained full-year guidance, projecting 2026 revenue to reachRMB51.3-53.0bn, with revenue from continuing operations to grow by 18-22%YoY. Adj. net profit margin is expected to remain stable. Mgmt. indicated plans toraise the guidance in due course based on future business developments.   CRDMO model to capture global blockbuster opportunities. Within thismodel, drug discovery and development services continuously funnel projectsto downstream. The Company delivered +420,000 new compounds over thepast 12 months, converted 83 projects from R to D, and added nine new PhIIIand commercial projects in 1Q26. This funnel model, which covers a widerange of therapeutic areas and a large customer base globally, allows theCompany to identify industry trends and build capacity in advance. As aresult, this approach has enabled WuXi AppTec to capitalize on commercialopportunities for multiple global blockbuster products, including oral COVID-19 drugs and peptides/ small-molecule GLP-1 drugs. Benefiting from oralGLP-1 drugs, revenue from small molecule D&M surged by 80.1% YoY in1Q26, creating a new growth engine for the Company. As a natural extensionof CRDMO model, TIDES saw 1Q26 revenue growth impacted by the pacingof product deliveries, resulting in a modest 6.1% YoY increase. However,based on a robust backlog, mgmt. expects full-year revenue for this segmentto grow by ~40%, reflecting mgmt's confidence in the TIDES business.   Continued capacity expansion. Driven by growing global demand, WuXiAppTec plans to bring the construction of new Changzhou site ahead ofschedule, which will house both small molecule and TIDES capacity. Mgmt.targets the total solid-phase synthesis reactor volume to reach 130k liters bythe end of 2026, up from 100k liters at the end of 2025. Despite theuncertainties from the Middle East, the strategic cooperation agreementsigned with the Saudi government last Oct is proceeding as planned, a keycomponent of the Company's long-term strategy to build global capabilitiesand capacity. Mgmt. forecasts 2026 capex to be RMB6.5-7.5bn, representinga YoY increase of 17.3-35.4%. We believe that WuXi AppTec's mature globalCRDMO network and ongoing expansions will further reinforce its leadingposition in the global pharmaceutical outsourcing industry.   Maintain BUY. To factor into the strong momentum of small molecule D&Mbusiness, we lift our earnings forecasts, expecting revenue to grow by 15.2%/16.3%/ 14.8% YoY (for continuing operations: 20.6%/ 16.3%/ 14.8% YoY)and adj. net profit to grow by 26.2%/ 18.0%/ 15.8% YoY in 2026E/ 27E/ 28E,respectively. Hence, we raise our DCF-based TP from RMB133.00 toRMB143.00 (WACC: 9.39%, terminal growth: 2.00%; both unchanged).
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  • 发布机构:

    CMB International Capital Corporation Limited

  • 发布日期:

    2026-04-29

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报告摘要

  药明康德(603259)

  WuXi AppTec released better-than-expected 1Q26 financial results. Revenuegrew by 28.8% YoY to RMB12.4bn with continuing operations revenue increasingby 39.4% YoY, while adj. non-IFRS attributable net profit surged 71.7% YoY toRMB4.6bn. 1Q26 revenue/ adj. net profit represent 24.1%/ 25.6% of our full-yearforecasts, respectively, significantly higher than the historical average of 18-20%.As of 1Q26, backlog for continuing operations grew by 23.6% YoY (+29% YoY ifexcl. FX fluctuations) to RMB59.8bn, with new orders signed in 1Q26 growing byover 25%. Mgmt. maintained full-year guidance, projecting 2026 revenue to reachRMB51.3-53.0bn, with revenue from continuing operations to grow by 18-22%YoY. Adj. net profit margin is expected to remain stable. Mgmt. indicated plans toraise the guidance in due course based on future business developments.

  CRDMO model to capture global blockbuster opportunities. Within thismodel, drug discovery and development services continuously funnel projectsto downstream. The Company delivered +420,000 new compounds over thepast 12 months, converted 83 projects from R to D, and added nine new PhIIIand commercial projects in 1Q26. This funnel model, which covers a widerange of therapeutic areas and a large customer base globally, allows theCompany to identify industry trends and build capacity in advance. As aresult, this approach has enabled WuXi AppTec to capitalize on commercialopportunities for multiple global blockbuster products, including oral COVID-19 drugs and peptides/ small-molecule GLP-1 drugs. Benefiting from oralGLP-1 drugs, revenue from small molecule D&M surged by 80.1% YoY in1Q26, creating a new growth engine for the Company. As a natural extensionof CRDMO model, TIDES saw 1Q26 revenue growth impacted by the pacingof product deliveries, resulting in a modest 6.1% YoY increase. However,based on a robust backlog, mgmt. expects full-year revenue for this segmentto grow by ~40%, reflecting mgmt's confidence in the TIDES business.

  Continued capacity expansion. Driven by growing global demand, WuXiAppTec plans to bring the construction of new Changzhou site ahead ofschedule, which will house both small molecule and TIDES capacity. Mgmt.targets the total solid-phase synthesis reactor volume to reach 130k liters bythe end of 2026, up from 100k liters at the end of 2025. Despite theuncertainties from the Middle East, the strategic cooperation agreementsigned with the Saudi government last Oct is proceeding as planned, a keycomponent of the Company's long-term strategy to build global capabilitiesand capacity. Mgmt. forecasts 2026 capex to be RMB6.5-7.5bn, representinga YoY increase of 17.3-35.4%. We believe that WuXi AppTec's mature globalCRDMO network and ongoing expansions will further reinforce its leadingposition in the global pharmaceutical outsourcing industry.

  Maintain BUY. To factor into the strong momentum of small molecule D&Mbusiness, we lift our earnings forecasts, expecting revenue to grow by 15.2%/16.3%/ 14.8% YoY (for continuing operations: 20.6%/ 16.3%/ 14.8% YoY)and adj. net profit to grow by 26.2%/ 18.0%/ 15.8% YoY in 2026E/ 27E/ 28E,respectively. Hence, we raise our DCF-based TP from RMB133.00 toRMB143.00 (WACC: 9.39%, terminal growth: 2.00%; both unchanged).

中心思想

1Q26业绩超预期,小分子D&M成为核心增长引擎

药明康德2026年第一季度营收达124亿元(同比+28.8%),持续经营业务营收同比+39.4%,调整后归母净利润同比飙升71.7%至46亿元。业绩表现显著高于历史18-20%的季节性占比,显示公司正进入加速增长阶段。小分子D&M业务受益于口服GLP-1药物全球放量,营收同比暴增80.1%,成为全新增长引擎。

CRDMO漏斗模型与产能扩张巩固全球领导地位

公司通过CRDMO模式实现从药物发现到商业化生产的项目持续转化:第一季度新增420,000个化合物、转化83个项目至D阶段、新增9个III期及商业化项目。同时,常州新基地提前建设,2026年固相合成反应器总容积目标达13万升,全球化布局(沙特合作等)持续推进,进一步强化其作为全球医药外包龙头的竞争壁垒。


主要内容

1Q26业绩:小分子D&M驱动整体增长

  • 营收与利润表现:2026年第一季度营收124亿元(同比+28.8%),持续经营业务营收同比+39.4%;调整后归母净利润46亿元(同比+71.7%)。营收和净利分别占全年预测的24.1%和25.6%,显著高于历史均值18-20%。
  • 订单及指引:截至1Q26,持续经营业务在手订单598亿元(同比+23.6%,剔除汇率影响+29%),新签订单同比增速超25%。管理层维持全年营收513-530亿元指引(持续经营业务增速18-22%),并计划根据后续业务进展适时上调。

CRDMO模型捕捉全球重磅药物机遇

  • 漏斗效应:过去12个月交付超42万个新化合物,将83个项目从R阶段转化至D阶段,1Q26新增9个III期及商业化项目。该模型覆盖广泛治疗领域和全球客户群,使公司能提前识别行业趋势并布局产能。
  • 小分子D&M爆发:受益于口服GLP-1药物(如GLP-1口服小分子)放量,小分子D&M业务1Q26营收同比增80.1%。TIDES业务受交付节奏影响仅增6.1%,但基于强劲在手订单,管理层预计全年TIDES营收增速约40%,体现信心。

持续产能扩张

  • 国内产能:常州新生产基地建设提前,将同时容纳小分子和TIDES产能。2026年底固相合成反应器总容积目标达13万升(2025年底为10万升)。
  • 全球布局:沙特政府战略合作按计划推进,为公司长期全球能力建设关键一步。2026年资本开支预计65-75亿元(同比+17.3-35.4%),成熟全球CRDMO网络和持续扩张将巩固行业领导地位。

维持买入评级,上调目标价

  • 盈利预测调整:基于小分子D&M强劲动能,上调2026-2028年营收预测至523.6亿/608.8亿/699.0亿元(持续经营业务同比增长20.6%/16.3%/14.8%),调整后净利润分别增长26.2%/18.0%/15.8%至188.8亿/222.8亿/258.1亿元。
  • 目标价:DCF估值目标价从133元上调至143元(WACC 9.39%,终端增长率2.0%不变),当前股价110.57元对应29.3%上行空间。调整后PE分别为17.5x/14.8x/12.8x(2026E/27E/28E)。

总结

本报告基于药明康德2026年第一季度超预期财务表现,系统分析了其增长驱动力。核心结论如下:

  • 短期动能强劲:1Q26营收和利润均大幅超越历史季节性规律,小分子D&M业务(+80.1%)成为最大亮点,口服GLP-1药物商业化需求持续放量。
  • 中长期逻辑清晰:CRDMO漏斗模型确保项目持续从早期研发向商业化阶段转化,支撑长期收入增长;全球产能扩张(常州提前建设、沙特合作)和TIDES业务全年约40%增速预期进一步增强成长可见度。
  • 估值与评级:公司凭借领先的CRDMO平台、全球化能力及行业景气度提升,具备持续超额收益潜力。上调目标价至143元,维持“买入”评级,对应2026年调整后PE约17.5倍,在历史估值中枢下方,具备安全边际。
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