中心思想 全球需求驱动业绩加速增长，CDMO里程碑交易奠定长期动能 基于2025年财务数据，Pharmaron北京营收同比增长14.8%至141.0亿元，经调整净利润同比增长13.0%至18.2亿元，增速较2024年显著提升。收入与利润分别较预期高出0.5%和0.7%，符合市场预期。管理层预计2026年营收同比增长12%-18%，已考虑汇率约3个百分点的负面影响。核心驱动力来自全球前20大药企客户收入暴增29.4%，远超公司整体水平，以及欧洲客户收入增长27.4%，体现全球研发外包需求的全面回暖。 小分子CDMO商业服务实现关键突破，礼来合作重塑增长预期 2026年3月礼来向Pharmaron投入2亿美元用于口服GLP-1药物Orforglipron的DP（制剂）商业化生产合作。此协议不仅将带来未来可观的增量收入（2026年贡献有限），更标志着Pharmaron的CDMO平台已通过顶级药企的严格质量体系认证。加之其API（原料药）设施已通过FDA检查，首个美国创新API项目于2025年四季度获批，公司小分子CDMO业务未来三年增速将超越其他业务线，成为增长主引擎。 主要内容 财务业绩回顾：增长加速，利润率稳健提升 营收与利润双升：2025年营收141.0亿元（+14.8% YoY），经调整净利润18.2亿元（+13.0% YoY），增速较2024年的6.4%和-15.6%大幅改善。毛利率从34.2%提升至34.8%，预期在2026-2028年进一步升至35.8%-37.5%。 分业务驱动：实验室服务新订单同比增长约12%；小分子CDMO新订单同比增长约13%，新增24个临床III期及15个PPQ/商业化项目；临床开发新订单增速超过公司平均，显示国内临床需求企稳及市场份额提升。 全球客户需求扩张：战略客户渗透与CDMO管线推进 顶级客户表现：全球前20大药企收入同比增长29.4%，远高于14.8%的公司平均。欧洲客户收入同比增长27.4%，得益于有效的市场进入战略和CDMO项目稳步推进。 订单增长趋势：2025年新签订单同比增长超14%，延续2024年超20%的强劲增势，表明全球对研发与生产外包的需求持续扩大。 小分子CDMO商业服务突破：礼来合作与商业化能力证明 里程碑式DP协议：与礼来就口服GLP-1药物Orforglipron签署商业化制剂生产协议。礼来投资2亿美元支持Pharmaron技术能力建设，未来合作范围有扩大潜力。该协议将产生大量增量收入，并作为公司全球化拓展的强有力背书。 商业化API能力：绍兴和宁波的API设施均已通过FDA检查，首个美国创新API项目于2025年四季度获批。基于DP合作及管线进展，预计未来三年小分子CDMO增速将快于其他业务线。 盈利预测与估值：上调目标价，维持买入评级 财务预测上调：CMBIGM将2026/27年营收预测分别上调1.98%/1.65%，毛利率预测上调1.29/1.39个百分点，经调整净利润预测上调1.38%/0.53%。 估值与评级：基于DCF模型（WACC 9.32%，终端增长率2.0%），将目标价从38.08元上调至39.00元，维持“买入”评级。预测2026-2028年经调整净利润同比分别增长18.7%/17.7%/16.5%。 总结 Pharmaron北京2025年业绩全面加速，全球客户需求扩张及小分子CDMO商业化突破是核心驱动力。与礼来的制剂生产合作协议是标志性事件，不仅锁定了未来高增量收入，更向全球市场证明了公司CDMO平台符合顶级药企质量标准。公司API能力也已通过FDA认证，商业化管线日益丰富。管理层预计2026年营收增长12%-18%（受汇率负面3ppt影响），CMBIGM预计实际增长16.4%，且未来三年经调整净利润复合增速约17.6%。当前股价27.98元，对应2026年调整后PE为23.8倍，目标价39.00元具备39.4%上行空间。全球研发与生产外包需求回升背景下，Pharmaron正从实验室服务到商业化生产全链条受益，尤其CDMO业务将凭借头部客户背书和产能优势进入加速增长期。

中心思想 CDMO需求强劲驱动2026年增长，药明康德业绩超预期 本报告核心观点认为，药明康德2025年财务表现强劲，收入同比增长15.8%（持续经营业务增长21.4%），调整后非IFRS净利润同比增长41.3%，均超出市场预期。强劲的CDMO需求是主要驱动力，体现在2025年底持续经营业务积压订单同比增长28.8%（固定汇率下34%），其中TIDES业务积压订单加速增长，小分子D&M业务也呈现加速态势。早期业务（小分子药物发现、测试、生物学）在2025年出现明显复苏迹象，收入降幅收窄或转正，预计2026年将继续受益于全球生物技术融资复苏。公司大幅增加资本支出以扩大全球产能（2026年capex预计65-75亿元，肽固相合成反应器容量扩至13万升），彰显对未来制造需求的信心。基于此，报告上调目标价至133元（+42%上行空间），维持买入评级。 盈利预期上调，估值具有吸引力 报告将2026-2028年盈利预测显著上调，调整后净利润分别较此前预测提高28.5%/31.7%，主要反映了更高的收入增长预期和利润率改善。当前估值水平（2026年调整后PE 15.6x）相对于强劲的盈利增长（2026-2028年调整后净利润复合增速约16.5%）具有吸引力。DCF估值模型（WACC 9.39%，终端增长率2.0%）得出的目标价133元，对应约15%的估值提升空间。 主要内容 业绩概览与关键财务数据 2025年全年业绩：收入454.6亿元（+15.8% YoY），持续经营业务收入增长21.4%；调整后非IFRS净利润149.6亿元（+41.3% YoY），分别超预期2.7%和18.2%。 2026年指引：管理层预计2026年收入513-530亿元，持续经营业务收入增长18-22%，调整后非IFRS净利率保持稳定。 盈利预测上调：报告将2026-2028年调整后净利润预测分别上调28.5%/31.7%/新增2028年预测，反映需求前景改善。 核心业务分析：CDMO需求强劲 积压订单持续增长：截至2025年四季度末，持续经营业务积压订单达580亿元（+28.8% YoY，固定汇率+34%）。尽管增速较三季度末的45.8%有所放缓，但基于庞大的绝对基数，仍显示出全球客户需求的持续旺盛。 TIDES业务加速：TIDES积压订单同比增长20.2%（三季度末为17.1%），积压订单规模约200亿元。管理层预计2026年TIDES业务将实现30-40%的固定汇率同比增长。 小分子D&M业务：报告测算其他业务（主要包含小分子D&M）积压订单同比增长33.8%，预计2026年也将实现加速增长。 早期业务复苏与全球产能扩张 早期业务收入改善： 小分子药物发现服务：2025年全年收入同比下降3.8%（2024年下降28.7%），下半年仅下降2.2%。 测试业务：2025年全年收入同比增长4.7%（2024年下降8.0%），下半年增长8.8%。 生物学业务：2025年全年收入同比增长5.2%（2024年下降0.3%）。 随着全球生物技术融资复苏，预计2026年复苏势头将持续。 全球产能扩张计划： 2025年资本支出55.4亿元（+38.5% YoY），扭转2024年下降趋势。 2026年资本支出预计65-75亿元（+17.3%~35.4% YoY），支持全球产能建设。 计划将肽固相合成反应器容量扩至13万升，反映多肽/寡核苷酸药物制造需求的激增。 估值与评级 目标价调整：基于DCF模型，目标价从123.35元上调至133.00元（WACC 9.39%，终端增长率2.0%），对应42%上行空间。 盈利预测：预计2026E/27E/28E持续经营业务收入增速分别为19.1%/15.7%/13.4%，调整后净利润增速分别为19.9%/16.0%/13.6%。 评级：维持买入评级。 风险因素：需关注地缘政治风险、行业监管变化、全球生物技术融资波动等敏感性因素（DCF敏感性分析显示，WACC变动1%或终端增长率变动0.5%时，估值波动区间为110-173元）。 总结 药明康德2025年业绩表现强劲，收入与利润均超预期，核心驱动力来自CDMO业务的持续旺盛需求。积压订单高增、TIDES业务加速、早期业务明显复苏，共同构成了2026年增长的坚实基础。公司大幅扩大资本开支以扩张产能，特别是多肽领域的布局，彰显对中长期需求的信心。报告上调盈利预测和目标价至133元，当前估值（2026年调整后PE 15.6x）与未来2-3年约16%的净利润复合增速相比具备吸引力，维持买入评级。主要关注点在于全球生物技术融资趋势、地缘政治不确定性以及产能扩张的执行效果。

　　迈瑞医疗(300760) 　　In2024,Mindray reported revenue of RMB36.7bn(+5.1%YoY)and attributablenet profit of RMB11.7bn(+0.7%YoY).GPM dropped by1.1ppts YoY to63.1%,primarily due to1)pricing pressure on IVD reagents and mid-to low-end medicalequipment,2)weaker IVD testing demand following DRG2.0implementationand inter-hospital recognition of test results.The proportion of revenue from IVDreagent declined in4Q24.The Sino-US trade frictions may raise costs for US-sourced raw materials in2025E,while Mindray is actively seeking substitutes toprotect margins.In1Q25,Mindray’s revenue fell by12.1%YoY to RMB8.2bn,mainly due to1)over20%YoY decline in domestic revenue,as revenuerecognition lagged behind procurement recovery,2)a high overseas revenuebase in1Q24(up nearly30%YoY),resulting in slow1Q25overseas growth of4.3%YoY. 　　Steady growth from overseas.In2024,overseas revenue grew by21.3%YoY to RMB16.4bn,accounting for44.7%of total revenue(+6.0ppts).Ex-North America revenue rose26%YoY to RMB13.8bn,with Asia-Pacificcontinuing as the growth engine.Mindray achieved further breakthroughs inhigh-end markets,with high-end strategic customers contributing14%ofoverseas revenue.With enhanced localization and installations of high-endproducts such as the MT8000,we expect the overseas revenue to grow bya mid-teens percentage in2025E.As the US contributed only~6%ofMindray’s total revenue,the impact of trade frictions may be moderate.Diversified manufacturing across13countries and proactive inventorymanagement should help mitigate related risks. 　　Domestic market remained under pressure.In2024,domestic revenuedecreased by5.1%YoY to RMB20.3bn.Revenue from PMLS and MISsegments fell31%YoY and2%YoY,respectively,due to weak hospitalprocurement.According to IQVIA,China’s medical equipment marketdecreased12.3%YoY in2024.Policy headwinds including DRG2.0,inter-hospital recognition of test results,and reagent price cuts further weighedon IVD revenue.IQVIA estimated a decline in the biochemical market andflat growth in immunology market in2024.Therefore,Mindray’s domesticIVD revenue increased1%YoY in2024.However,Joinchain data shows a67.5%YoY increase in medical equipment bidding value in1Q25,indicatingpotential recovery of domestic medical equipment procurement.Weanticipate the revenue recovery will occur in2H25E,primarily due to thetime lag between the bidding process and revenue recognition. 　　Maintain BUY.Given the uncertainties of the timeline of domesticprocurement recovery and trade frictions,we revise down our earningsforecasts.We expect revenue and attributable net profit to grow9.4%and6.5%YoY,respectively,in2025E.Based on a9-year DCF model,we adjustour TP to RMB249.19(WACC:9.2%,terminal growth rate:3.0%).

　　药明康德(603259) 　　WuXi AppTec reported impressive 1Q25 financial results. Revenue increased by21.0% YoY to RMB9.65bn, with revenue from continuing operations rising by23.1% YoY to RMB9.39bn. Adjusted non-IFRS net profit surged by 40.0% YoY toRMB2.68bn. Both revenue and net profit continued the quarterly improvementtrend seen throughout 2024, which further accelerated significantly in 1Q25. Asof the end of 1Q25, the Company’s backlog grew by 47.1% YoY to RMB52.33bn.Despite ongoing macro uncertainties, mgmt. has reaffirmed its full-year guidance,projecting a 10–15% YoY increase in revenue from continuing operations andexpansion in the adjusted non-IFRS net profit margin. 　　TIDES business gained momentum with strong growth. WuXi AppTec’sTIDES business experienced strong growth 1Q25, with revenue soaring187.6% YoY to RMB2.24bn, an acceleration from the 70.1% growth in 2024.According to mgmt., the growth was driven by the ramp-up of new capacitiesand contributions from oral GLP-1 programs. TIDES backlog more thandoubled, increasing by 105.5% YoY as of 1Q25, providing a solid foundationfor sustained growth. The Company remains on track to expand its peptidecapacity to over 100k liters by the end of 2025. Hence, Mgmt. continued toexpect TIDES revenue to grow more than 60% YoY in 2025. 　　Early-stage business remained under pressure with signs of moderaterecovery. Revenue from Biology segment grew 8.2% YoY in 1Q25, marking asecond consecutive quarter of positive growth, indicating a recovery in clientdemand for drug discovery services. In Chemistry segment, small-molecule drugdiscovery revenue declined 7.1% YoY, an improvement from the 28.7% YoYdrop in 2024. Testing segment remained affected by pricing pressure. Lab testingrevenue slid 4.9% YoY (vs. -8.0% YoY in 2024), with safety assessment revenuefalling 7.8% YoY (vs. -13.0% YoY in 2024). Mgmt. noted that pricing appeared tohave reached a trough, although a meaningful recovery will still take time. 　　Strengthening shareholder returns amid market uncertainties. WuXiAppTec’s Board of Directors has proposed a series of shareholder returninitiatives, including maintaining a 30% annual cash dividend payout ratio,issuing a one-time RMB1bn special dividend in 2025, introducing the interimdividend plan in 2025, and repurchasing and cancelling RMB1bn A-shares(announced on March 17). In addition, the Company announced a secondRMB1bn A-share repurchase and cancellation plan on April 8, which has nowcommenced. Combined, the proposed dividends and share repurchaseprograms total nearly RMB6bn, equivalent to 62% of 2024 attributable netprofit, underscoring WuXi AppTec’s strong commitment to shareholder return. 　　Maintain BUY. Due to the macro uncertainties such as the US-China tradewar, we revise down forecasts and now expect revenue from continuingoperation business to grow by 13.3%/14.9%/15.9% YoY and adjusted nonIFRS net income to grow by 9.7%/17.5%/15.9% YoY in 2025E/ 26E/ 27E,respectively (previously: 14.4%/15.2%/16.3% and 11.7%/19.0%/+16.1%YoY). We thus cut our DCF-based TP from RMB94.05 to RMB77.22 (WACC:9.42%, terminal growth: 2.00%; both unchanged). Our estimates are higherthan Bloomberg consensus, reflecting our confidence in earnings resilience

　　联影医疗(688271) 　　In 2024, United Imaging’s revenue declined 9.7% YoY to RMB10.3bn, withattributable net profit decreasing 36.1% YoY to RMB1.3bn mainly due to thechallenging domestic market environment. Due to delays in equipment renewalpolicies and prolonged industry rectification, the domestic medical equipmentmarket contracted by 12.4% YoY in 2024, according to IQVIA. Despite thechallenging environment, United Imaging’s GPM improved by 1.5 ppts YoY,supported by higher proportion of revenue from mid-to-high-end products (+0.9 pptsequipment GPM) and services (+1.7 ppts GPM from scale/cost optimization). In1Q25, United Imaging achieved turnaround in earnings with revenue andattributable net profit increasing by 5.4% and 1.9% YoY respectively, indicating arecovery in the domestic market. 　　Overseas business remained robust. In 2024, overseas revenue grew 35.1%YoY to RMB2.3bn, accounting for 22.0% of total revenue (+7.3ppts YoY). ExNorth America revenue rose ~28% YoY to RMB1.6bn, accounting for ~71% ofthe total overseas revenue. United Imaging continued to expand in Europeanand emerging markets, with installation breakthroughs in France, Germany, andemerging markets such as South Africa, Morocco, and Brazil in 2024. Its marketshare in India rose to second place. The strong momentum of overseasbusiness persisted in 1Q25, and we expect overseas business to remain a keygrowth driver in 2025E. With North America contributing only ~6% of totalrevenue, the impact of trade frictions may be limited. Proactive inventorymanagement and global supply chain diversification will further help mitigatethe risks of trade tensions. 　　Domestic business was under pressure but signs of recovery haveemerged. In 2024, domestic revenue fell by 17.5% YoY to RMB8.0bn.However, the Company’s market share in domestic imaging equipment(excluding ultrasound and DSA) increased significantly, ranking first in marketshare, with significant share gains (+5ppts) in the high-end market. Domesticprocurement recovered strongly in 1Q25, with the domestic medical equipmentbidding value up 67.5% YoY, according to Joinchain. Given the long revenuerecognition cycle for large equipment, we expect meaningful recovery ofdomestic revenue from 2H25E. 　　Services income grew fast. Services revenue increased by 26.8% YoY toRMB1.4bn in 2024, with revenue contribution growing to 13.2% (+3.8ppts YoY).However, there remains a significant gap compared to GE Healthcare’s 34%service revenue share in 2024, indicating large room for improvement. As of2024, the Company’s global installed base exceeded 34,500 units. Withexpanding installed base, we expect service revenue to maintain rapid growth. 　　Maintain BUY. Given the uncertain pace of domestic market recovery andongoing trade frictions, we revise down our 2024-2027E revenue forecasts to aCAGR of 18.1%.Thus, we adjust our TP to RMB149.83, based on a 9-year DCFmodel (WACC: 8.2%, terminal growth: 4.0%)

　　药明康德(603259) 　　WuXi AppTec reported a YoY revenue decline of 2.73%, to RMB39.2bn, and a2.5% decrease in adjusted non-IFRS net profit, to RMB10.6bn. However,earnings showed encouraging improvement throughout 2024, resulting in apositive revenue and profit growth in 4Q24. The TIDES business remained theprimary growth engine, with full-year revenue up by 70.1% YoY. The Company'sbacklog as of year-end 2024 expanded significantly, growing 47% YoY toRMB49.3bn. Notably, TIDES backlog experienced a substantial 103.9% YoYincrease in 2024. Fuelled by robust order book, management offered a positiveoutlook for 2025, forecasting 10-15% YoY revenue growth in continuingoperations and further enhancement of the adjusted non-IFRS net profit margin. 　　Strong order growth bolsters future revenue visibility. WuXi AppTec'sbacklog at end-2024 grew by a significant 47% YoY, reaching RMB49.3bn.This represents an acceleration from the 35.2% growth seen at the end of3Q24. Positive trends were evident across segments. CDMO businesssecured 25 new Ph3 and commercial projects in 2024 (vs 20 added in 2023).Biology segment returned to positive revenue growth in 4Q24, posting YoYand QoQ increases of 9.3% and 9.2%, respectively, signaling an improvingtrend in early-stage R&D demand. Furthermore, revenue from Top20 globalpharma clients rose by 24.1% YoY (excl. COVID related projects), expeditingfrom the 23.1% growth in 9M24. These metrics underscore the increasingvisibility of the Company's future revenue. Given the positive outlook for futuredemand, the Company plans to boost capex by 75%-100% YoY in 2025 toRMB7-8bn. 　　TIDES business sustains strong growth trajectory. TIDES revenue in2024 climbed 70.1% YoY, with backlog expanded by 103.9% YoY. Underlyingdemand for polypeptide manufacturing remains robust in the market. TheCompany's polypeptide capacity reached 41k liters by end-2024, with plansfor a further increase exceeding 100k liters by late 2025, demonstrating WuXiAppTec’s commitment to meeting the growing customer demand. Mgmtanticipates TIDES revenue growth of over 60% YoY in 2025. 　　Ongoing commitment to shareholder returns. Amidst macroeconomicuncertainties in 2024, WuXi AppTec strengthened its commitment toshareholder returns. The Company completed RMB4.0bn in sharerepurchases and cancellations in 2024 and maintained a dividend payoutratio of 30% for the year. To further enhance returns, mgmt announced a onetime special dividend of RMB1.0bn, alongside a 2025 interim dividend. Mgmtalso indicated plans to repurchase RMB1.0bn of A-shares in 2025. 　　Maintain BUY. We raise our TP from RMB78.51 to RMB94.05 (based on a10-year DCF model with WACC of 9.42% and terminal growth of 2.0%), tofactor in the earnings recovery. We forecast the continuing operation revenueto grow by 14.4%/ 15.2%/ 16.3% YoY and adjusted non-IFRS net income togrow by 11.7%/ 19.0%/ +16.1% YoY in 2025E/ 26E/ 27E, respectively. Our2025E/ 26E/ 27E forecasts of adjusted non-IFRS profit are 6.9%/ 14.9%/19.6% higher than consensus.

　　联影医疗(688271) 　　United Imaging’s 9M24 revenue declined by 6.4% YoY to RMB6,954mn, with 3Q24revenue down by 25.0% YoY to RMB1.6bn. This downturn was primarily due to achallenging domestic market environment, marked by stringent industry regulationsand delays in equipment renewal projects. Attributable net profit in 9M24 decreasedby 36.9% YoY to RMB671mn, with net profit margin falling by 4.7 ppts. Despitethese near-term challenges, United Imaging maintained its R&D expenditures andactively pursued expansion in international markets, which impacted profitability inthe third quarter. Looking forward, as the implementation of equipment renewalprojects has gradually picked up pace, United Imaging's revenue and net profitmargins are expected to significantly improve in 2025E, in our view. 　　Robust overseas growth momentum. In 9M24, United Imaging’s overseasrevenue grew 36.5% YoY to RMB1,404mn, accounting for 20.2% (+6.35 ppts)of total revenue. This accelerated growth continued into the third quarter, withrevenues increasing by 51.7% YoY to RMB471mn. Strong performances werenoted across North America, the Asia-Pacific region, and emerging markets. AsUnited Imaging continues to enhance its overseas localization and servicecapabilities, we believe it is poised to strengthen its global competitiveness,better navigate geopolitical challenges, and sustain rapid growth internationally. 　　Strong growth in recurring revenue. In 9M24, revenue from maintenanceservices increased by 27.3% YoY to RMB967mn, accounting for 13.9% (+3.7ppts) of the total revenue. With a global installed base now exceeding 31,000units, United Imaging's service revenue contribution remains lower comparedto global industry leaders like GE Healthcare (32.9% in 2023) and Philips(27.7% in 2023). However, with the expanding installed base and an enhancedglobal service network, we expect United Imaging’s recurring revenue tocontinue its rapid increase, offering resilience against industry fluctuations. 　　Medical equipment renewal projects set to materialize. Mgmt. has notedthat medical equipment renewal projects began implementation in earlyOctober, with multiple procurement activities underway. Additionally, somepreviously delayed equipment procurements, halted due to policy uncertainties,have now restarted. These developments lay the foundation for a recovery inUnited Imaging’s domestic business in 4Q24 and 2025. However, due tostringent industry regulations, the procurement process has become moreprotracted. The installation and revenue recognition timelines for largeequipment are also relatively long. Consequently, the positive impact of thisprocurement rebound is expected to be primarily reflected in 2025, in our view. 　　Maintain BUY. We expect hospital procurement to recover from 2025 and weare optimistic about the Company's long-term growth potential driven by thecontinued import substitution and strengthened global competitiveness.Therefore, we revise up the terminal growth rate forecast from 3.0% to 4.0%.Based on a 9-year DCF model, we adjust the target price to RMB162.81(WACC: 8.3%, terminal growth rate: 4.0%).

　　迈瑞医疗(300760) 　　Mindray reported9M24revenue of RMB29.5bn,up by8.0%YoY.Attributable netprofit increased by8.2%YoY to RMB10.6bn.Revenue in3Q24grew by1.4%YoY to RMB9.0bn while attributable net profit decreased by9.3%YoY toRMB3.1bn.The slowdown in revenue growth can primarily be attributed tolackluster procurement activities in domestic public hospitals and weakeneddemand for IVD testing,particularly in lower-tier hospitals.Consequently,Mindray's domestic revenue fell by9.7%YoY in3Q24.Additionally,GPM in3Q24decreased by4.8pcts QoQ due to updates in accounting guidelines. 　　Domestic market remained under pressure,although signs of recoveryin procurement are emerging.1)IVD:Domestic revenue grew by17%YoYin9M24.Nationwide DRG implementation had a negative impact on thediagnosis demand in lower-tier hospitals which were the main contributors toMindray's domestic IVD revenue.To counter act this,Mindray activelyexpanded its IVD business into top hospitals through its TLA and IT solutions.We expect Mindray to install over150TLAs in2024E.2)MIS:Domesticrevenue grew by over10%YoY in9M24driven by the strong volume ramp-up of ultra-high-end Resona A20ultrasound system.3)PMLS:Domesticrevenue decreased by28%YoY in9M24.The decline was influenced by 　　environment.However,with accelerated issuance of special bonds,andstronger government support to address local debt issues,we expectdomestic equipment demand to recover in2025E. 　　Healthy growth in overseas business.In3Q24,Mindray’s overseasrevenue increased by18.6%YoY with strong performances in Europe(+29%YoY),APAC(+32%YoY)and LatAm(+25%YoY),although there was someweakness in the US market.Driven by breakthroughs in medium-to-largevolume labs,Mindray’s overseas IVD revenue increased by32%YoY in9M24,accounting for28%of total overseas revenue.Mindray hasaccelerated its overseas localization efforts.As of3Q24,Mindray launchedlocal manufacturing in9countries,8of which are related to IVD.Additionally,emerging businesses such as minimally invasive surgery(+50+%YoY),AED(+50+%YoY)and animal medical(+30+%YoY)grew significantly in9M24.These emerging businesses contributed over10%to Mindray’s overseasrevenue.We expect IVD and emerging businesses to become the primarygrowth drivers for Mindray’s overseas businesses. 　　Maintain BUY.We lowered our earnings forecasts with target price adjustedto RMB328.81(WACC:9.3%,terminal growth rate:3.0%).

　　药明康德(603259) 　　WuXi AppTec reported 3Q24 revenue of RMB10.46bn, slightly down 2.0% YoY,and attributable adjusted non-IFRS net profit of RMB2.97bn, down 3.2% YoY.Total non-COVID revenue and non-COVID Chemistry revenue growth reboundedto 14.6% YoY and 26.4% YoY, respectively, in 3Q24. Despite the challenginggeopolitical environment, mgmt. reiterated its revenue guidance of RMB38.3-40.5bn for 2024, indicating 2.7%~8.6% YoY non-COVID revenue growth.Additionally, mgmt. reiterated its commitment to maintaining an adjusted nonIFRS net profit margin consistent with the levels achieved in 2023. 　　Strong global competitiveness led to fast order growth. As of 3Q24, WuXiAppTec's backlog climbed to RMB43.82bn, representing a YoY increase of35.3%, maintaining the encouraging momentum of 33.2% YoY growth(excluding COVID-19 commercial projects) in 1H24. The rapid backloggrowth signified the enduring trust that global clients place in WuXi AppTec'shigh-quality and efficient services. This is further evidenced by a robust 23.1%YoY rise in revenues from global Top 20 pharmaceutical companies in 9M24,a notable acceleration from the 11.9% growth observed in 1H24.Management has indicated that 80% of the backlog is expected to convertinto revenue within the next 12 to 18 months, providing strong earningsvisibility for WuXi AppTec in 4Q24 and throughout 2025, in our view. 　　TIDES continues to exhibit strong growth. TIDES revenue grew by 71.0%YoY in 9M24, with the growth accelerating to 98.6% YoY in 3Q24. The TIDESbacklog as of 3Q24 saw a substantial YoY increase of 196%. In Jan 2024,WuXi AppTec expanded its peptide production capacity from 10k liters to 32kliters, with plans to expand to 41k liters by the end of 2024 and further to 100kliters by 2025. This ambitious expansion underscores WuXi AppTec'scommitment to meeting the rapidly growing global demand for peptideservices, positioning TIDES as the strongest growth driver for the Companythrough 2026. 　　Overseas peers struggle to compete with Chinese chemical CDMOs inthe medium term. In our in-depth report published on 21 Oct 2024, weanalyzed the business fundamentals of 30 companies from Europe, the US,and India engaged in API and chemical CDMO services. The findings revealthat these companies significantly trail WuXi AppTec in terms of businessscale and capacity. Specifically, most Indian peers primarily offer bulk andspecialty APIs, with limited capabilities in supporting innovative drugs R&D.Meanwhile, European firms, despite having an established pharmaceuticalmanufacturing base with several well-known chemical CDMOs, tend to focusmore on formulation instead of API. Their manufacturing sites, primarilylocated in Central and Western Europe, face higher labor costs compared toWuXi AppTec, further disadvantaging them in the competitive market. 　　Maintain BUY. Factoring in the positive trend of customer demand, we lift ourTP from RMB67.72 to RMB72.37 (based on a 10-year DCF model withWACC of 9.42% and terminal growth of 2.0%). We forecast revenue to growby -3.6%/ +11.4%/ +13.6% YoY and adjusted non-IFRS net income to growby -3.9%/ +11.9%/ +15.5% YoY in 2024E/ 25E/ 26E, respectively.

　　迈瑞医疗(300760) 　　Mindray achieved a revenue of RMB20.5bn in 1H24, marking an 11.1% increaseYoY, and reported an attributable net profit of RMB7.6bn, up 17.4% YoY. Despite theongoing regulatory adjustments in the healthcare industry and the delay in medicalequipment renewals projects, which have led to a cautious approach towards biddingand procurement activities in public hospitals, the revenue from domestic equipmentbusiness decreased by 12% YoY. However, thanks to the rapid growth of the IVDbusiness and the domestic high-end/ultra-high-end ultrasound business, Mindray stilldemonstrated strong resilience and steady growth. The increase in the revenue sharefrom IVD reagents and high-end ultrasounds drove the Company's gross margin upby 0.7 ppt YoY to 66.3% in 1H24. Additionally, Mindray announced a mid-termdividend plan, distributing a total cash dividend of approximately RMB4.9bn, whichrepresents a payout ratio of more than 65%, indicating an ongoing increase in thedividend payout. 　　Domestic equipment business faces pressure. In 1H24, the continued delayin bidding and procurement activities led to a 12% YoY decrease in revenue fromdomestic equipment business. Due to the high market share of Mindray's PatientMonitoring and Life Support (PMLS) products in China, the domestic businesswas significantly affected by the industry environment, with the PMLS segmentexperiencing a 7.6% YoY decrease in revenue, including about a 20% drop indomestic revenue. The Medical Imaging segment benefited from the volumeincrease of the first domestic ultra-high-end ultrasound Resona A20 and otherhigh-end ultrasounds, resulting in a 15.5% YoY revenue growth in this segment,with high-end and ultra-high-end ultrasound revenues increasing by over 40%. 　　Accelerating the shift towards consumables-related business. In 1H24, theIVD reagent business was minimally affected by domestic industry regulation,with revenue increasing by 28% YoY to RMB7.7bn, accounting for over 37% oftotal revenue. Domestic IVD revenue grew by over 25%, and domestic reagentrevenue increased by 30%, with reagent revenue representing over 80% ofdomestic IVD revenue. Internationally, Mindray successfully penetrated over 60overseas third-party chain laboratories in 1H24 and installed the first MT 8000TLA, driving a more than 30% YoY increase in overseas IVD revenue. We believethat the continuous increase in domestic diagnostic demand and theimplementation of IVD VBP are expected to help Mindray rapidly expand itsdomestic market share, while accelerated cooperation with high-end clients willsupport long-term rapid growth of the IVD overseas market. Additionally, theminimally invasive surgery business grew by 90% YoY in 1H24. The Company’sacquisition of APT Medical also filled the gap in its cardiovascular consumablesbusiness. Currently, consumables-related businesses led by IVD already accountfor over 50% of the Company’s domestic revenue. 　　Maintain BUY. We believe that industry regulation has not affected the essentialdemand for hospital procurement. As industry regulation becomes normalizedand equipment renewal policies are implemented, hospital procurement isexpected to gradually recover. Based on a 9-year DCF model, we adjust thetarget price to RMB 352.84 (WACC: 10.3%, perpetual growth rate: 3.0%).